JoesTeam.CA Triathlon | Duathlon - Benefiting - The Princess Margaret Cancer Foundation UHN

    RESEARCH UPDATE

    April 6, 2016



    A Research Update from Dr. Fei-Fei Liu - Scientific Director, Head and Neck Cancer (“HNC”) Research Team

    This year has seen significant advancements in Head and Neck Cancer research at the Princess Margaret Cancer Centre. Thanks to the immense generosity of Joe’s Team, the “Joe Finley Centre for HNC Research” was established in 2015 and is rapidly becoming an internationally recognized hub of scientific excellence. The Centre is comprised of over 80 clinicians and scientists whose groundbreaking research on innovative biological insights and treatment strategies are driving discoveries in personalized care, aiming to improve patient survival and quality of life.

    Since last year, our team, in collaboration with The Cancer Genome Atlas (funded by the US National Cancer Institute), published a landmark research article in one of the top scientific journals in our biomedical community, Nature. This publication described the detailed genetic analysis of a large group of Head and Neck Squamous Cell Carcinomas, identifying key genetic features that are associated with these cancers, and importantly, offering clues to possible new targets for individualized treatments.

    Refining tumour staging and predicting outcome is another critical aspect of personalized cancer medicine.  To that end, Dr. Brian O’Sullivan’s group led the research on changing the way oncologists stage and predict the prognosis for patients with Oropharyngeal Carcinomas that are caused by infections with the Human Papillomavirus.

    Furthermore, my team validated a micro ribonucleic acid signature in nasopharyngeal carcinoma biopsy tissues to help predict whether a patient’s cancer will metastasize following initial treatment. These research projects have significant implications for management of HNC at the Princess Margaret Cancer Centre and around the world.

    Our vision of “Achieving a future of Head and Neck Cancer cures with no toxicity” would not be possible without the enormous and invaluable contributions by the Joe’s Team fundraisers, volunteers and sponsors. Members of the Joe Finley Centre for HNC Research are all looking forward to participating in the 10th and final Joe’s Team event on Saturday, July 9th, 2016.  Together, we continue to strive for our collective goal of “Conquering Cancer in Our Lifetime” and honouring the amazing and inspirational Joe Finley.